Jolana Schmiedl
Global Medical Director CSL Behring, SwitzerlandPresentation Title:
Can inherited coagulopathies cause perinatal bleeding?
Abstract
Postpartum hemorrhage (PPH), also known as perinatal bleeding, remains the leading cause of maternal mortality worldwide. Despite significant advancements in the diagnosis and management of massive obstetric bleeding, PPH continues to account for approximately 25 percent of maternal deaths annually. It affects nearly 14 million women each year and results in the death of one woman every two minutes. This review aims to examine the role of coagulation factors in the pathophysiology of PPH, emphasize the importance of a multidisciplinary approach in obstetric care, and assess the impact of evidence-based treatment protocols on maternal outcomes. A comprehensive literature review was conducted, focusing on recent clinical studies and international guidelines related to PPH and coagulopathies. Particular attention was given to inherited bleeding disorders and their role in delayed diagnosis and management. My findings suggest that inherited coagulopathies are frequently underrecognized in obstetric settings, contributing to preventable maternal morbidity and mortality. Despite being largely preventable, PPH continues to pose a significant threat to maternal health globally. Addressing the role of coagulation disorders, enhancing diagnostic strategies, and implementing standardized treatment protocols are critical steps toward reducing maternal mortality and improving outcomes in obstetric care.
Biography
Dr. Jolana Schmiedl, DVM, has completed a
Master of Advanced Studies in International Health at the Swiss Tropical and
Public Health Institute (Swiss TPH) in Basel, Switzerland. Her academic and
professional focus lies in women’s health, particularly in relation
to coagulopathies—disorders affecting blood clotting. She is actively
involved in educating and connecting healthcare professionals who
work with bleeding disorders, with a strong emphasis on improving care and
awareness in women's health. Dr. Schmiedl has also contributed to the
scientific community through multiple publications on these topics.
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